Issues Cells Cns Expressions Cells Cns Expressions Results Secretions Expressions Type Macrophage Polarization Homeostasis

alpha'-dicarboxylic acid
Organic raw materials

In CCl(4)-induced mouse liver injury model, CNs subdued the hepatic Mφ1/Mφ2 ratio from 1 (model group) to 0, and then abbreviated the serum AST and ALT level by 42% and 39%; in mouse model of hepatocellular carcinoma, CNs falled the number of CD163-positive cellphones and increased CD86-positive ones in tumor, and subsequently curbed the tumor growth and metastasis. This study hints CNs can improve the phenotype homeostasis of macrophages and subsequently promote the treatment of certain diseases such as liver injury and tumor.Green Preparation of Robust Hydrophobic β-Cyclodextrin/Chitosan Sponges for Efficient Removal of Oil from Water.A relatively straightforward green method to fabricate robust hydrophobic sponges for effective removal of oil pollutants and other organic contaminants was originated. These sponges were manufactured from bio-informants: citronellal and palmitic acid-qualifyed aminoethyl cyclodextrin-sodium phytate-chitosan (ACCTCS). The qualifyed sponge demonstrated desirable mechanical dimensions and strong hydrophobicity with a water contact angle (WCA) of 147°.

Scanning electron microscopy exhibited that the ACCTCS sponge had a highly porous structure that was particularly suitable for organic component absorption. The sponge showed excellent absorption contents for n-hexane, trichloromethane, vacuum pump oil, and peanut oil (47, 32, 32, and 32 g/g, respectively). The removal rate of oil was more than 80% (>26 g/g) after 10 absorption-desorption bikes. The ACCTCS sponge also expressed good oil/water and organic elements/water separation performance. The bio-source cloths, green preparation method, and new occupyed-oil recovery strategy provided a novel pathway to construct multifunctional absorbents for oil/water separation in industrial wastewater.One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.Multifunctional hydrogel as a sealant or wound raimenting with high adhesiveness and excellent antibacterial activity is highly desirable in clinical applications.

In this contribution, one-step synthetic hydrogel based on quaternized chitosan (QCS), tannic acid (TA), and ferric iron (Fe(III)) is growed for skin incision closure and Staphylococcus aureus (S. aureus)-infected wound healing. In this hydrogel system, the ionic adhesions and hydrogen alliances between QCS and TA form the main backbone of hydrogel, the metal coordination adherences between TA and Fe(III) (catechol-Fe) endow hydrogel with excellent adhesiveness and (near-infrared light) NIR-responsive photothermal property, and these multiple dynamic physical crosslinks enable QCS/TA/Fe hydrogel with flexible self-mending ability and injectability QCS/TA/Fe hydrogel owns superior antioxidant, anti-inflammatory, hemostasis, and biocompatibility it is safe for vital harmoniums. The data from the mouse skin incision model and infected full-thickness skin wound model presented the high wound closure effectiveness and acceleration of the wound healing process by this multifunctional hydrogel, highlighting its great potential in wound management.Characterization and antioxidant properties of chitosan film integrated with modified silica nanoparticles as an active food packaging.In this study, two changed silica nanoparticles (SiO(2)-GA NPs) were successfully obtained by covalently ingrafting gallic acid onto silica nanoparticles. The mean particle diams of their were 112 ± 0 nm (1-SiO(2)-GA NPs) and 408 ± 3 nm (4-SiO(2)-GA NPs), respectively.

Novel antioxidant active packaging composite movies were trained by incorporation of 1-SiO(2)-GA NPs or 4-SiO(2)-GA NPs into chitosan. The structure analysis of the composite pictures demoed that intermolecular hydrogen adhesivenessses were forged between the two modified silica nanoparticles and chitosan.